The majority of the publications are cantered around leprosy, covering various aspects such as epidemiology, clinical management, diagnostic tools (including high-resolution ultrasound and antibody testing), treatment strategies, and the impact of interventions like Multi-Drug Therapy (MDT).

They are number of collaborators nationally, Internationally. Nireekshana recognizes the strength of collaboration. They collaborate with other researchers across multiple studies, suggesting a network of experts involved in leprosy, HIV and NTD research research.

The research spans clinical studies, epidemiological surveys, histopathological analyses, immunological studies, and the application of advanced diagnostic techniques (like ultrasonography and ELISA assays). This multi-dimensional approach helps in comprehensively understanding various facets of leprosy and other diseases.

There is a publication discussing the management of leprosy during the COVID-19 pandemic, reflecting adaptation and recommendations for handling endemic diseases during global health crises.

Some publications indicate longitudinal studies (e.g., cohort studies) that track outcomes over time, providing insights into disease progression, treatment responses, and long-term complications.

Collaborations with international organizations and institutions within India underscore a concerted effort to address leprosy comprehensively and globally.

Introduction of high-resolution ultrasound as a diagnostic tool highlights efforts to innovate and improve diagnostic accuracy in leprosy, especially for neuropathic complications.

Publications include recommendations and guidelines for improving leprosy management, influencing policy and clinical practice in India.

These insights collectively underscore a robust research effort aimed at advancing knowledge, improving diagnostic capabilities, optimizing treatment strategies, and ultimately enhancing the quality of care for individuals affected by leprosy, HIV and other diseases.

Several studies delve into the immune response to Mycobacterium leprae, the bacterium causing leprosy. This includes investigating how host immune cells recognize and respond to the pathogen, leading to varying disease outcomes such as tuberculoid or lepromatous leprosy.

Research explores genetic factors influencing susceptibility to leprosy, focusing on host genetic polymorphisms associated with immune response genes like HLA (Human Leukocyte Antigen) loci. Understanding these variations helps in elucidating why some individuals are more prone to developing leprosy.

Studies analyze cytokine profiles in leprosy patients, examining the balance between pro-inflammatory and anti-inflammatory cytokines. Imbalances in cytokine production contribute to disease pathology and clinical manifestations.

Investigations into how Mycobacterium leprae interacts with macrophages, the primary host cells, shed light on bacterial survival strategies and the immune evasion mechanisms employed by the pathogen.

Exploration of epigenetic changes in leprosy patients elucidates how environmental factors and host genetics influence gene expression patterns relevant to disease progression and clinical outcomes.

esearch into microRNAs (miRNAs) involved in leprosy pathogenesis identifies specific miRNAs that regulate immune responses or bacterial survival within host cells, potentially serving as biomarkers or therapeutic targets.

Investigation of molecular mechanisms underlying drug resistance in Mycobacterium leprae informs strategies for optimizing treatment regimens and combating emerging resistance patterns.